Jane Adams is an American actress who portrays Dr. Melinda Karnofsky Crane, on NBC comedy series Frasier.
Adams was born in Washington, D.C., the daughter of Janice Adams, an administrative assistant, and William Adams, an engineer. She has a younger brother, Jonathan, and was raised in Wheaton, Illinois and Bellevue, Washington. Adams attended the University of Washington, where she studied political science, and the Cornish College of the Arts, where she took theater. She attended the Juilliard School's Drama Division (1985-1989, Group 18) where she graduated with a Bachelors of Fine Arts degree in 1989. Adams then performed theatre at the Seattle Repertory Theatre.
In 1998, she starred in Happiness with Philip Seymour Hoffman playing the role of Joy, a sensitive single woman who is struggling with life. She and the cast won many ensemble awards. The next year, Adams got a recurring role on the hit comedy series Frasier from 1999 to 2000. She played Dr. Mel Karnofsky, who became Niles Crane's second wife. She also had a role in the film Mumford. In 2001, she was in the independent film titled Songcatcher, with Janet McTeer. She and the cast won a Sundance Special Jury Prize. In 2007, she appeared in The Sensation of Sight and The Brave One opposite Jodie Foster, Naveen Andrews, Terrence Howard, and Mary Steenburgen. She co-starred in the HBO series Hung opposite Thomas Jane from 2009-11. In 2015, she is Dr. Brooke Powell in the reboot of the film Poltergeist.